Immunoglobulin (Ig) in multifocal motor neuropathy (MMN): update on evidence for Ig treatment in MMN
نویسندگان
چکیده
منابع مشابه
High-dose intravenous immunoglobulin therapy in multifocal motor neuropathy.
We treated five consecutive patients with multifocal motor neuropathy (MMN) with high-dose intravenous immunoglobulin (IVIg). Four patients had increased levels of anti-asialo-GM1 IgM and two of anti-GM1 IgM as well; one patient had no reactivity. We treated them twice with 0.4 g/kg IVIg for 5 consecutive days at a 2-month interval, followed by maintenance infusions up to 6 to 12 months. All pa...
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The mismatch negativity (MMN) component is an event-related potential (ERP) that can be elicited by any change in the acoustic environment, and it is related to memory-based, automatic processing mechanisms, and attentional capture processes. This component is well defined in the auditory modality. However, there is still a great controversy about its existence in the visual modality. This pape...
متن کاملMultifocal motor neuropathy: current concepts and controversies.
Multifocal motor neuropathy (MMN) is now a well-defined purely motor multineuropathy characterized by the presence of multifocal partial motor conduction blocks (CB), frequent association with anti-GM1 IgM antibodies, and usually a good response to high-dose intravenous immunoglobulin (IVIg) therapy. However, several issues remain to be clarified in the diagnosis, pathogenesis, and therapy of t...
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BACKGROUND Cognitive deficits are considered core symptoms of the schizophrenia. Cognitive function has been found to be a better predictor of functional outcome than symptom levels. Changed mismatch negativity (MMN) reflects abnormalities of early auditory processing in schizophrenia. Up to now, no studies for the effects of aripiprazole on MMN in schizophrenia have been reported. METHODOLOG...
متن کاملMultifocal motor neuropathy.
We report the case of a patient with multifocal motor neuropathy. Electrophysiological studies showed typical multifocal conduction blocks, but the search for anti-GM1 antibodies was negative. This case provide the heterogeneity of this clinical entity.
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2014
ISSN: 0009-9104
DOI: 10.1111/cei.12505